MANAGEMENT TEAM

Eric Broyles, J.D.

Founder & CEO

Trained as a corporate attorney, Eric Broyles has been a serial entrepreneur for over 15 years and has led breakthrough developments in pharma/healthcare. Eric began his career at Skadden, Arps, Slate, Meagher, & Flom LLP and then served as Senior Counsel to AOL and AOL Time Warner. After practicing law for 10 years, Eric jumped to the business side first helping to build Gerson Lehrman Group, the largest expert network firm in the world with a valuation exceeding $1billion. He is the Founder of ExpertConnect, which manages a global network of 150,000 subject matter experts including 60,000 healthcare/pharma experts who consult with many of the largest healthcare investors in the US. Eric led the launch of a clinical trial and the first ever development of a transdermal patch with proven delivery of Vitamin D, Iron and Zinc through the skin with a top university in England who licensed one of Eric’s companies a proprietary formulation for this innovation. Eric is a summa cum laude graduate of the University of Cincinnati where he majored in Marketing and Management and was Valedictorian of his class. He graduated from the University of Virginia School of Law where he currently serves as President of its Alumni Council. He is a patent holder and serves on the Board of Trustees for the University of Cincinnati Foundation.

Paul Nguyen, MD, MBA, FASTRO

Adviser, Medical Affairs

Dr Paul Nguyen is a Professor of Radiation Oncology at Harvard Medical School, The Baldwin-Politi Distinguished Chair in Oncology at Brigham and Women’s Hospital, and Co-Leader of the Genitourinary Disease Center at the Dana-Farber/Brigham Cancer Center. An internationally-recognized expert in prostate cancer research and clinical care, he contributed to the academic development of the underlying Nanocan NEST technology and has significant experience testing novel drugs in large phase III multicenter randomized trials. He also served as a primary medical adviser to Augmenix which was acquired for $650 million by Boston Scientific and previously was a consultant at the Boston Consulting Group. Dr Nguyen received his AB with honors from Harvard College, his MD from Harvard Medical School, and completed his residency at the Harvard Radiation Oncology Program where he was Chief Resident. He also earned an MBA from MIT Sloan.

Philmo Oh, MD, PhD

Chief Scientific Officer

Dr. Philmo Oh is vice president of Piedmont Radiation Oncology, providing radiation oncology services at Novant Health where he specializes in treatment of gastrointestinal, thoracic, and hematologic malignancies. He has extensive research experience in the tumor microenvironment and responses to radiation and immunotherapy for which he was awarded numerous grants and fellowships. Dr. Oh received his BA in Economics and BA in Biology from The University of North Carolina at Chapel Hill. He completed his MD and PhD in Molecular Oncology and Immunology at New York University. Dr. Oh completed his internship at Mt Sinai and residency in Radiation Oncology at NYU during which time he was Chief Resident.

Adam Shilling, PhD

Chief Development Officer

Adam has a PhD in Toxicology and 22 years of pharmaceutical industry experience spanning all phases of clinical and nonclinical drug development. Adam was most recently at Prelude Therapeutics as VP of Early Development and Regulatory Affairs, where he built the regulatory department, successfully submitted and opened seven INDs in oncology, contributed to the growth of the clinical organization, and served as interim toxicology and clinical pharmacology lead. He also was clinical study director for oral and IV programs, leading 3 clinical trials in solid tumors and hematologic malignancies. Before Prelude, Adam was Executive Director of Global Regulatory Affairs at Incyte Corporation where he was global lead for multiple early and late-stage programs in oncology, hematology and inflammation, including the NDA submission and approval of Jakafi in acute GVHD and contributing to development and NDA/MAA approvals for Jakafi in myelofibrosis and polycythemia vera, Olumiant in rheumatoid arthritis, Tabrecta in NSCLC, and Pemazyre in cholangiocarcinoma. Prior to Incyte, Adam was at Wyeth (now Pfizer), contributing to the discovery and development of programs in infectious diseases, women's health, and neuroscience, including NDA for Pristiq in major depressive disorders.

Dave Krasne, MBA

CFO

Dave is an entrepreneurial professional with more than 25 years of finance and operating experience. He is the founder and serves as a Director of Sentire Medical Systems, a National Science Foundation funded medical device company focused on patient safety; a co-founder of RedNest Partners, a private investment firm; and a co-founder and Director of ExpertConnect, a professional services firm matching a variety of enterprises with subject matter experts. Dave’s prior experience includes: VP at the Riverside Company, a lower middle market private equity firm; Chief Operating Officer at Professional Sports Publications, a publisher of game day programs for professional and collegiate teams and events; and Principal in Merrill Lynch’s Global Private Equity division. Prior to receiving his MBA, Dave worked in Investment Banking at Merrill Lynch executing mergers, acquisitions, and corporate finance transactions for clients in the technology and financial services industries. Dave earned a BS in Finance from Penn State University and an MBA from The Anderson School at UCLA.

SCIENTIFIC ADVISORS

Dr. Paul Wallner

Dr. Paul Wallner is a radiation oncologist (DO) by training and is the former Senior Vice President for Medical Affairs at GenesisCare USA, Inc., the USA division of an international cancer care and research organization. He also served as Associate Executive Director of the American Board of Radiology, with responsibility for initial certification and maintenance of certification of US Radiation Oncologists. Dr. Wallner previously served as Professor and Chair of the Department of Radiation Oncology (DRO) at Robert Wood Johnson Medical School/Camden (NJ), Professor, Vice Chair of the DRO, University of Pennsylvania Perelman School of Medicine, and Chief of the Clinical Radiation Oncology Branch of the National Cancer Institute. Dr. Wallner has served on the Board of Chancellors of the American College of Radiology (ACR), the Board of Directors of the American Society for Therapeutic Radiology and Oncology (ASTRO) and the Board of Chancellors of the American College of Radiation Oncology (ACRO). He has served as President of the American Cancer Society, NJ Division, Chairman of the NJ Commission on Cancer Research, and Chairman of the Council on Public Health of the Medical Society of NJ.

Major General Elder Granger, MD, US Army (Retired)

Dr. Granger, an oncologist, is president and CEO of THE 5Ps, LLC, a health care, education and leadership consulting organization. Dr. Granger served in the U.S. Army for over 35 years before retiring in 2009 and was the Deputy Director and Program Executive Officer of the TRICARE Management Activity, Office of the Assistant Secretary of Defense (Health Affairs). In this role, he was the principal advisor to the Assistant Secretary of Defense (Health Affairs) on DOD health plan policy and performance. He oversaw the acquisition, operation and integration of TRICARE/DOD’s managed care program within the Military Health System. Dr. Granger currently serves on the boards of directors of Cigna Corporation (NYSE:CI) and DLH Holdings Corporation (NASDAQ: DLHC).

Brian I. Rini, MD, FASCO

Dr. Rini is a recognized leader in genitourinary oncology, kidney cancer, and clinical drug development. He is the inaugural Chief of Clinical Trials for the Vanderbilt-Ingram Cancer Center. At Vanderbilt, he is an Ingram Professor of Medicine and leads kidney cancer clinical research efforts, and focuses on expanding oncology clinical research operations and training opportunities in clinical cancer research across the board. Prior to Vanderbilt, Dr. Rini served as the Director of the Genitourinary Cancer Program and Professor of Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. He also served as Chair of the Oncologic Drugs Advisory Committee for the FDA.

Jonathan T. Yang, M.D., Ph.D.

Dr. Yang is a radiation oncologist who specializes in treating tumors of the central nervous system and metastatic tumors in the body. He is the Director of Metastatic Disease and Developmental Therapeutics in the Department of Radiation Oncology at the University of Washington. He previously served as the Director of Metastatic Disease Service in the Department of Radiation Oncology at Memorial Sloan Kettering Cancer Center (MSKCC) where he was also a member of the Early Drug Development Service. Dr. Yang has extensive clinical experience and knowledge in combination treatments using radiation and novel drug therapies based on tumor biology. He has led several important clinical trials to improve the treatment and outcomes for patients with metastatic cancer.