Nanocan is the exclusive worldwide license holder of Nanoparticle Encapsulated Smart Technology (NEST™)

Read about the licensing of its NEST™ technology here.

NEST™ technology forms the foundation of Nancan's drug-delivery platform. Nanocan’s product development pipeline includes treatments for several cancer indications. Nanocan’s NEST™ drug delivery platform can be employed to sustainably deliver different drug payloads – including immunotherapy drugs, chemotherapy, and phytomedicines – precisely to disease sites or targets, with greater therapeutic efficacy and lower toxicity / side effects. This work leverages the abscopal effect, where treating a tumor at one site leads to regression of tumors elsewhere in the body.

The capabilities of Nanocan’s NEST™ formulations include:

  • Targeting – To locally attack specific tumors.
  • Imaging – To track NEST™ throughout the body.
  • Drug Payloads – To deliver targeted and sustained doses of therapeutic(s) to the tumor site.
  • Convenience – NEST™ combination treatments can be delivered in a single intervention.

Nanocan’s approach has the promise of treating both local and metastatic disease, reducing treatment time and cost, improving patient convenience, and increasing access to cancer treatment.

Nanocan’s NEST™ presents several advantages
over currently-available treatments, including:

  • Enhanced bioavailability
  • Sustained drug delivery, which reduces dosing frequency, improves patient compliance, and decreases incidence of any side effects
  • Improved biodegradation and clearance from the body
  • Image-guided monitoring of distribution and treatment response via Computed Tomography and Magnetic Resonance Imaging

Additionally, the Company’s NEST™ formulations can be employed to deliver
a variety of drug payloads, including phytomedicines, to potentially treat
certain respiratory diseases and pain.

Nanocan’s NEST™ products will be available in three distinct formulations optimized for treatment of specific cancer indications:

NEST™ SEEDS are implanted in tumors that are difficult to access or
are highly concentrated, such as:

  • Prostate
  • Pancreas
  • Liver

NEST™ GEL can be applied to larger, superficial areas and is optimized for the following cancer indications:

  • Skin
  • Breast
  • Cervical
  • Oral
  • Head & Neck

NEST™ Inhalation formulation enables access to hard to target cancer indications such as:

  • Lung
  • Brain (Glioblastoma)